Cause of disease of _ of characteristic that the crooked mushroom of jejunum suffers from diarrhoea

Cause of disease of _ of characteristic that the crooked mushroom of jejunum suffers from diarrhoea
The crooked fungus of jejunum is the important pathogen of enteritis, in recent years, report of this disease increases day by day. Detection of fungus this it leads to be 3%- 18% generally in crowd, with September and infant and pre-school children of 14 months old it bends morbidity, fungus of enteritis to be highest, bacterium's detection rate can be up to 40%.
The crooked fungus of jejunum is fungus of living away from home normally in poultry, domestic animal, some birds, beast's intestine. From the excrement and urine of animals such as the dog, chicken, turkey, pigeon, aquatic bird, ox, sheep, pig, horse,etc., can isolate a fungus. It can be dyed after milk, chicken, pork or drinking water polluted that people eat.
This fungus produced cholera and a kind of intestines toxin and caused a disease, mainly infringe jejunum, ileum and colon, cause the mucous membrane of intestines and organize inflammation, even membrane inflammation in septicaemia and heart.
This disease is 3- 5 days in incubation period, mainly shown as and generated heat, suffered from abdominal pain, suffered from diarrhoea, been disgusting, vomited, stool take the form of water sample, mucus or glue blood so that blood specimen relieve oneself. The clinical manifestation of the light case is similar to viral gastroenteritis, the clinical manifestation of the serious disease case can be like fungus dysentery or ulcer colitis, a few cases can present the poisoning huge colon, , the mesenterium lymphnoditis, appendicitis, meningitis, pneumonia, septicaemia, cholecystitis, urine way infection or tubercle erythema that false membrane colitis, lower digestive tract bleed Carry HLA-B27 person who organizes antigen of compatibility, reactive arthritis can happen.
Diagnose a disease for being fast, can gather and suffer from diarrhoea the patient's excrement and urine direct slide mirror and examine and look for the crooked fungus, dyeing the method specifically has the following two:
(1) The orchid decoration method of the leather: Fetch fresh the intersection of excrement and urine and direct slide, mirror examine after getting blue to dye leather, 40% sensitiveness its, the specificity is 99%.
(2)1% are alkaline to reply red decoration method: Fetch the fresh excrement and urine (the desirable excrement and urine sample that keeps within 24 hours in culture medium too) ,Scribble one layer on glass slice of year, it is fixed to heat slowly, then soak for 1- 2 minutes in 1% alkaline solution, rinse with the distilled water, the blotting paper is blotted, observe under 1000 times of microscopes, find the very thin one, if shape, S shape, volution or person who banters some shape bacteria that the gull spreads the wings, it is positive. The mirror is examined by 5- 10 minutes, the persons who have not seen this kind of bacterium are negative. The sensitiveness of this law is 90%, the specificity is 98%.
The definite diagnosis of this disease, the bacterium depending on the excrement and urine or blood trains, operate specifically: Inoculate the sample including through the ages mouldly and plainly, glue more funguses plain B and culture medium of oxygen benzyl ammonia pyrimidine of the first, second and third, put in 5% of the oxygen, 10% of the carbon dioxide, 85% of the nitrogen environments and train, then is isolated and trains from the suspicious colony, and then react according to biochemistry and the agglutinate test of serum is appraised.
The patients can mostly heal by oneself, but the persons who are not treated, 20% may recur. Supplement the liquid, correct to desiccate to lack proper care with the electrolyte, in order to treat the basic measure of a disease. If condition relatively serious, can pay antibacterial treatment.
Mostly to erythromycin, tetracycline, amino sugar glucoside antibiotic, quinoline promise ketone in view of pathogens ' Such as the pyrrole piperazine acid or Fluorine piperazine acid) , chlorine forest very mould plain, chloromycetin and furazolidone,etc. sensitive, can select erythromycin (30mg k g d) first treat, Or gentamicin (the held up ining type is cleared up slice slowly in the stomach, auspicious Bake by name of goods, once and 2 slices, 2 times a day, clothes of an hour) after the meal of morning and evening ,5 1 course of treatment in day, can also it selects Fluorine for use to be piperazine sour, etc in the intersection of piperazine and acid, pyrrole.
Because 5%- 92% of the bacterial strain can produce - inner amide enzyme, most penicillin, very beginning spore's fungus plain type medicine are invalid.
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