The scientist discovers that increases three kinds of genes of the probability of senile dementia
Britain and French scientist find 3 newly Plant with the intersection of Alzheimer and disease ' Senile dementia) Relevant genes, make the mankind take a great step again in the course of overcoming this kind with wide influence and endangering the great disease. Before this, scientists found a kind of gene related to this kind of disease only in 1993.Three kinds of genesBritain is from many universities More than 80 researchers are right to come from 8 countries 1 . 6 ten thousand healthy persons and senile dementia patients carry on the genetic scanning, then compare with the genetic difference between two kinds of persons. They find, the gene which is called Clusterin and PICALM is increasing and suffering from the gene of the probability of senile dementia.The French scientist is right to come from 5 countries 1 . 5 ten thousand healthy persons and senile dementia patients find after scanning the gene, the gene which is called CR1 is increasing and suffering from the gene of the probability of senile dementia too. French scientist has found Clusterin too.The research report on finding these three kinds of genes is published in Britain>Magazine.Researchers say, the senile dementia cases of 1,000 may relate to Clusterin gene, 900 relate to PICALM, 4 relates to CR1. In 1993, the scientist found 20 related to genetic APOE to the case of 25.Britain>Claim on the 7th, the research of Britain is the senile dementia gene studies of the largest scale since the dawn of human civilization.Of great significanceLeader that Britain studies, the intersection of university and the intersection of nerve and psychological Julie of science of heredity professor Williams, Cardiff of Britain, claim discovery this genetic discovery most important about senile dementia since the 1993.British researchers say, Clusterin and PICALM all have function of protecting the brain, but they can morph, to lose protective action,even " L The brain protector becomes a brain saboteur " .Williams says : " If we can be through treating the adverse factor of removing these genes, can cut down the ill number of people by 2,000. "Count, reveal the whole world have exceed, perplex by senile dementia by 2600 people Wan. It is estimated until 2050, the ill number of people is over 1 hundred million.This kind of disease can't be cured at present, there is not a good treatment method, the existing medicine just postpones time when the disease appears.Williams says, if can dispel the adverse factors of these three kinds of genes of new discovery, can prevent 10 in Britain every year alone Ten thousand people suffer from senile dementia. Williams says, already the great interest has emerged in the study on them in the drugmaker.Study more The British charity organization " L Study the trust foundation in senile dementia " R Director Rebecca Wood says : " In a situation that we have not found yet to contain such malignant disease, this finds that may bring numerous new thinkings, enhance coorperation and bring other benefits. "People thought in the past inflammation appearing in senile dementia patient's brain was a result of this kind of disease, however, discover newly, this kind of inflammation may be a pathogenic main reason, instead of the result. This treats the possibility increase of senile dementia with aspirin and these fragrant common antiinflammatory agents of Lip river of cloth.Researcher plan, launch further studying next year, research object up to 6 people Wan. Members of seminar Michael and Owen say, this research shows, it perhaps have other genes that which cause senile dementia.He draws an analogy and says : " We have seemed to fish with a net and pull some fish out with the fishing net all the time. We know that there are more fish in water, can drag for them with more close fishing network. "
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