Scientist find itch cell develop ideal alleviate itching medicine

Scientist find itch cell develop ideal alleviate itching medicine
The intersection of Sina and scientific and technological the intersection of news and the intersection of Beijing time and August 8 news, according to the intersection of foreign countries and the intersection of media and report, the intersection of health and back-scratcher, these are the thing that all people will go through every day . But do you know the arcane truth among them? The American scientist is through the finding, a group of cells have played a key role in this course, they will send paying special attention to itching and reminding information to the brain.
In the experiment course, the researchers of U.S.A. St.Louis University of Washington have destroyed this kind of cell in mouse's body. The result finds, the itch sense of the mouse is lightened, but perceive painful abilitying has not been influenced. This research impels the scientist to march towards a new goal that may be realized, namely develop the even more ideal alleviating itching medicine.
Generally, worm bite and whom anaphylaxis cause it itches to be can through scratch or take some resist ergamine medicines to drive away. What merits attention is, though some people scratch body too, fail, relieve in the daily life confirming cancer, chronic renal failure,etc. to be that many kinds of disease cause to itch sense vigorously by some, it is even the same after taking anaesthetizing antalgesic.
In fact, it is very difficult for us to pain and itch and separate. The research that is carried on before this reveals, a plurality of neural thorough fares may have something to do with the two. Publish on Publish on the 6th >The first confirmation of research report on the magazine, have and itch the relevant particular cells of sense in the spinal. The spinal, this string, expressway will turn towards the brain " L Transport " R Itching feels information. The intersection of forest and university, Vic of N.C. State, soak letter can medical center itch Gill, expert of sense, while being famous Inviting west Po to link very expresses : " It is really too exciting. This item comprehensive to study and undoubtedly open up a new field. "
2007, University of Washington anaesthetize study associate professor, chief the intersection of researcher and ZhouFeng Chen (Feng old week, transliteration) Find genetic GRPR related to itching for the first time. ZhouFeng Chen,et al. find when in with make object that itch it keep in touch, GRPR gene comparatively " L Lazy " Mouse pay special attention to not lasting number of times to last mouse. But this can not be proved, the spinal nerve cell with this kind of gene and itches the relevant particular cells of sense. As to related to sense of pain gene, spinal nerve cell acting the important role likewise.
This time, Chen ZhouFeng's research group injects a kind of neural toxin that can search GRPR receptor into mouse's spinal. GRPR receptor made one and berthed the location to click. During about two weeks, the neural toxin killed about 80% of the cells which contain GRPR. Before injecting the neural toxin, the mouse often scratches the body. After injecting, Chen ZhouFeng lets the mouse contact many kinds of materials making it itch. Because a large amount of " L Itch cells " R Killed, the stressing and itching the number of times of them shows a tendency to plummet, sometimes even behavior of paying special attention to itching of dead stop.
Not a large amount of mice " L Itch cells " R Disappearance fall into numb state. Researchers find, their sport machine can still keep normal through a series of experiment, it is the same to the response that keenlies feel that is heated and pressed and produced. In the experiment, while receiving various pressure, the mouse will shake the tail or draw back the claw son.
Invite west Po to link very pointing out, this is not that only one conveys and itches the passway of sense information to the brain. As to the thing that whether GRPR gene will present the similar behavior in the human body, the scientist is still unable to provide an accurate answer. At present, researchers have been looking for and itching the relevant particular receptors of sense, hope that understands finally how to prevent them from conveying to the brain " Scratch me " R Signal,and then not help relieve a little by type itch.
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