The scientist finds that treats the new hopes of self-closing disease and schizophrenia

The scientist finds that treats the new hopes of self-closing disease and schizophrenia

Davies website of branch school of University of California report recently, the researchers of this school found a kind of new brain albumen which is called SynDIG1 recently, play an essential role to forming and development that is touched suddenly. It is reported, this discovery will promote the understanding of human cognitive ability and brain function disorder, bring the new hope for the treatments of diseases such as self-closing disease, schizophrenia,etc.. It is here that the relevant research results are issued January 14 >On the magazine .
It is a kind of complicated chemical signal system to touch suddenly, are responsible for the communication among the nerve cell, have important function on study, memory, cognition,etc.. It will cause the brain function to be disorderly to touch suddenly out-of-balancely, result in suffering from diseases such as the self-closing disease, schizophrenia,etc.. A most one touch, serve as a kind of neurotransmission glutaminic acid suddenly in the brain. Past research revealed, adjusted and controlled the glutaminic acid receptor (AMPA receptor) ,It is essential for the exchange among the nerve cell .
Pharmacology assistant professor Elva and Diatz with university Davies branch school in the state leads a research group, pass a kind of prediction genetic (tmem90b) correctly Analysis,last membrane albumen, be named by SynDIG1 (if you can't touch, if you can't split up, induce it by products genetic suddenly) as . Under the help of molecule neurobiologist and electricity physiologist, they isolate cells from the neuron of body of sea horse of the mouse, carry on a series of test, in order to understand the function of this albumen.
Test indicate SynDIG1 and AMPA realize in the intersection of forming and location that touch suddenly clicking, existing at the same time, this indicate, should plant albumen early stage formed to touch essential suddenly; Study, find, express competence, can change quantity and quality that touch suddenly through control SynDIG1 in the nerve cell still: Reduce SynDIG1 to express, it will be lighter but less to touch suddenly; If strengthen SynDIG1 to express, it will be riper, steadier to touch suddenly. This indicate to touch forming, development and life-span,etc., there is essential function suddenly SynDIG1.
Diatz thinks, SynDIG1 is likewise important to the old and new nerve cell, it will influence neural development, have important relation with some neural diseases, perhaps will come a lot of brain diseases can be defined as touching disease suddenly again. The next step, researchers will test the function of SynDIG1 on intravital mouse. (Liu HaiYing ) (Source : Science and Technology Daily )
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